Due to the limited availability of bone allografts, which are donor-derived bone materials used for surgical reconstruction, doctors often depend on autografts and synthetic alternatives for bone repair and regeneration. Autografts, taken from the patient’s own body, are considered the gold standard because of their excellent biological compatibility and ability to promote natural bone healing. However, they come with significant drawbacks such as limited donor site availability, increased surgical time, risk of infection, and postoperative pain. On the other hand, synthetic bone substitutes—made from materials like calcium phosphates, bioactive glass, or polymers—offer an unlimited supply but often lack the biological properties required for complete integration and remodeling with natural bone. These limitations create a critical need for a new class of bone replacement materials that are safe, cost-effective, and capable of mimicking the natural structure and function of human bone. Such materials should ideally support cell growth, encourage vascularization, and integrate seamlessly with existing bone tissue.